spectronaut (version 17.3 Search Results


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Biognosys spectronaut
A) Timeline for microglia (top) and neuron (bottom) differentiation from iPSCs. B) Staining of iPSC-Neurons and iPSC-Microglia. C) Overview of the proteomic workflow, including cell lysis, protein digestion, and analysis with data independent acquisition microflow chromatography and variable width windows (vw) using the ZenoTOF 7600 platform with the M-Class HPLC. DIA data was searched using the panHuman library in <t>Spectronaut</t> v17 for protein identification and quantification. R scripts were used for bioinformatic analysis.
Spectronaut, supplied by Biognosys, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A) Timeline for microglia (top) and neuron (bottom) differentiation from iPSCs. B) Staining of iPSC-Neurons and iPSC-Microglia. C) Overview of the proteomic workflow, including cell lysis, protein digestion, and analysis with data independent acquisition microflow chromatography and variable width windows (vw) using the ZenoTOF 7600 platform with the M-Class HPLC. DIA data was searched using the panHuman library in Spectronaut v17 for protein identification and quantification. R scripts were used for bioinformatic analysis.

Journal: bioRxiv

Article Title: Investigation of Neurons and Microglia from APOE3 Induced Pluripotent Stem Cells using Data-Independent Acquisitions on a ZenoTOF 7600

doi: 10.1101/2025.11.02.686128

Figure Lengend Snippet: A) Timeline for microglia (top) and neuron (bottom) differentiation from iPSCs. B) Staining of iPSC-Neurons and iPSC-Microglia. C) Overview of the proteomic workflow, including cell lysis, protein digestion, and analysis with data independent acquisition microflow chromatography and variable width windows (vw) using the ZenoTOF 7600 platform with the M-Class HPLC. DIA data was searched using the panHuman library in Spectronaut v17 for protein identification and quantification. R scripts were used for bioinformatic analysis.

Article Snippet: All data files were analyzed using Spectronaut (version 17.3.230224.55965; Biognosys) applying spectral library searches.

Techniques: Staining, Lysis, Data-independent acquisition, Chromatography